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A PGK-neomycin resistance cassette replaced exons 2, 3, and 4. Northern blot analysis on spleen RNA from homozygous mice confirmed that no mRNA was expressed from this allele and immunoblot analysis on bone marrow derived cell lines from homozygous mice demonstrated an absence of encoded protein. (J:35785)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
