An IRES-lacZ cassette was inserted into exon 1. An adjacent loxP flanked neomycin resistance gene was removed in ES cells prior to blastocyst injection, leaving a single loxP site in the final allele. (J:67965)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count