Insertion of loxP sites flanking exon 3. A loxP flanked neomycin/thymidine kinase cassette in intron 3 was removed by transient expression of Cre recombinase in ES cells prior to blastocyst injection. (J:57315)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count