Deletion of exons 32 and 33, encoding the "z" alternative splice exons as follows: A lox-P flanked neomycin cassette replaced exons 32 and 33, and was excised in ES cells prior to blastocyst injection via Cre-mediated recombination. The final allele has a single loxP site in place of the two exons. (J:55407)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
Recessive
1
4
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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