The insertion of the pGT1.8TM secretory trap vector, containing a beta galactosidase reporter gene, occurred in an intron interrupting the neuropilin-2 coding sequence at cDNA position 2069 nt (amino acid Pro-680). The insertion site is located one-third of the way into the MAM domain of neuropilin-2. This mutation appears to be a loss of function. (J:60158)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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