The integration of gene trap vector pGT1.8TM occurred in an intron of the netrin 1 gene. The mutant allele is likely to be hypomorphic rather than null, since some of the wild-type transcripts are present, presumably by splicing over the inserted sequences. (J:37125)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
Recessive
1
2
80

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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