Arose spontaneously in a stock derived from an irradiated founder in Germany in 1981. Molecular analysis of the coding region in nackt mice revealed a 118 bp deletion involving the end of exon 6 and almost all of exon 7. Western analysis of skin from homozygous mutant mice indicated that no stable protein is produced. (J:69924, J:108004)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Radiation induced
Intragenic deletion
Recessive
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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