The transgene consists of the fusion product between the human genes TCF3 and HLF, as cloned from a translocation t(17;19) event. It was positioned downstream the SV40 promoter and an IGH enhancer, which drives expression in both B and T lymphoid lineages. (J:55022)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count