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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
Amyotrophic Lateral Sclerosis 1
USH2A c.8559-2A>G
Cystic Fibrosis
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Gene editing
Prnp
tm1Cwe
Alias:
Prnp trn
1Zrch
Prnp
0
Zurich I
Zurich line
Prnp
-
Zrch 1 Prnp
0
Prnp
tm1ZH1
Zrch Prnp
0
PrP
C
-KO
Prn-p
0
Prnp
0
PrP
C
Zrch-1
PrP
0
Prnp
tm1Zrch
PrnpZH1
ZrchI Prnp-
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Basic Information
Phenotypes
References Literature
A 552 bp fragment of the coding region contained within exon 3 was replaced with a 1.1 kb cassette containing the TK promoter followed by the neomycin gene. (J:472, J:83401)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
1888773
129S7/SvEvBrd-Hprt1+
Targeted
Insertion, Intragenic deletion
--
1
10
313
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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