The entire coding region of the gene, which is a single exon, was deleted and replaced by a construct containing the sequences for a lacZ gene and a loxP-flanked PGK-neomycin resistance gene cassette. This allele, Gja7tm1.1Kni, was derived when cre was expressed, resulting in the removal of the neomycin resistance gene. (J:63214)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count