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Male C3H/HeH mice received a fractionated dose of (3 + 3) Gy X-rays. Mitotic studies of G-banded chromosomes show that this mutation is associated with a paracentric inversion extending from 15D2 to 15F. Expression of Trps1 which is 0.8Mb proximal to the proximal breakpoint of this inversion is markedly reduced while expression of no other candidate genes near the break points are affected. (J:103253, J:121991, J:141036, J:155838)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
