A single loxP site was inserted 5' to exon 6 and a PCK-neomycin selection cassette followed by an additional loxP site was inserted 3' to exon 7. The insertion did not have any effect on the normal expression of the gene (data not shown). (J:46387)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count