The Ft mutation is the result of a transgene integration into mouse chromosome 8. The transgene integration event resulted in a deletion of 1.6 Mb of genomic sequences, covering coding regions for six genes. Among these are the genes included in the entire IroquoisB (IrxB) gene cluster. (J:44450, J:76079)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F2
--
Intergenic deletion
Semidominant
--
--
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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