Exons 12 throught 46 cannot be detected by PCR and are likely deleted, with the possibility of a large DNA insertion in their place. Northern blot analysis of brain RNA derived from homozygous mice demonstrated that an aberrant smaller transcript was expressed from this allele. Southern blot analysis indicated that a deletion or rearrangement of part of the gene had occurred in mutant mice. (J:26733, J:104061, J:120587)
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基础信息

模型ID
品系来源
等位基因类型
突变
遗传方式
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相关疾病
参考文献
BALB/cByJ
Spontaneous
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1
4
8

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标签摘要:
hm: 纯合子
ht: 杂合子
cn: 条件基因型
cx: 复合型:涉及多基因组
tg: 转基因
ot: 其他:半合子、不确定...
(F): 雌性
(M): 雄性
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N: 正常表型
(#): 上标括号内为相关疾病数量
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