A neomycin selection cassette replaced exons 1 and 2, which encode the first 166 amino acids, including the initiator methionine and 46 residues of the homeodomain. An absence of transcript was determined via in situ hybridization of the ventral diencephalon region in homozygous mutant embryos. (J:58996)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion, Intragenic deletion
Semidominant
1
2
12

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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