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A genomic fragment containing exons 2 and part of 3 was replaced with a lacZ gene with a splice acceptor site and neomycin selection cassette. RT-PCR analysis demonstrated that the mutation eliminated expression of the wild-type transcript, and whole-mount embryo staining studies revealed that beta-galactosidase is expressed from this allele. (J:62025)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
