A hygromycin expression cassette was inserted into exon 15 at codon 1638. The hygromycin cassette was inserted in the same transcriptional orientation as the Apc gene. A 182 kDa truncated protein is stably expressed from this allele. (J:55416)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count