A hygromycin resistance gene was inserted into exon 18, at codon 528, of the gene. No transcript for the targeted gene was detected on Northern blots of RNA extracted from testes of homozygous mutant mice. No protein product for the targeted gene was detected on Western blots of protein extracted from testes of homozygous mutant mice. (J:51921)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Targeted
Insertion
--
1
4
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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