This allele is the result of an insertion of a full length early transposon, fusing exon 1 to the 3'LTR of the ETn. Northern analysis of adipose tissue RNA showed that the insertion provided alternative splice acceptor and polyadenylation sites producing fusion RNAs between the first exon and the retrovirus and precluding the expression of RNA from the coding sequence of Lep. (J:40727)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
SM/Ckc-Fbxw4Dac
Spontaneous
Transposon insertion
Recessive
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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