Insertion of a PGK-neomycin resistance cassette introduced two loxP sites flanking exon 3 and the inserted cassette. Exon 3 contains phosphorylation target serine/threonine residues. Future deletion of exon 3 with cre recombinase would result in mRNA whose exons 2 and 4 are connected in frame. (J:58367)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count