A neomycin resistance cassette replaced the translation initiation site and its downstream sequence in exon 2. Northern blot analysis and western blot analysis confirmed the absence of expression from this allele (data not shown). Immunocytochemical studies did not detect protein in hippocampal coronal sections of homozygous mutant adult mice. (J:34606)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
Insertion, Intragenic deletion
--
1
--
21

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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