A lacZ neomycin cassette disrupted the exon encoding the seven-transmembrane-helix domain. Immunoblots of membrane preparations of cerebella from homozygous mutant mice showed no detectable native protein using antibodies against the C-terminal and N-terminal parts of the protein. (J:21644)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count