An nLacZ gene is fused in-frame to the DNA sequences encoding the first 13 amino acids, resulting in a disruption of the gene and expression of nLacZ under the transcriptional regulation of the endogenous promoter. A neomycin resistance cassette, RNA polymerase II promoter and 3' sequence of the HPRT gene were introduced after the reporter gene. (J:36716, J:39308, J:92799)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
2
38

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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