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Exon 1 was replaced by a construct containing lacZ and neo. The deleted coding sequence encodes the entire N-terminal dimerization domain and a portion of another domain showing homology to either the human POU-A subdomain or human B-domain. Western blot analysis showed an absence of encoded protein in homozygous mutant embryos. Beta-galactosidase was expressed under the control of the endogenous promoter. (J:58079)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
