The random insertion of a transgene into the Unc5c gene resulted in a ~8.5 kb genomic deletion at the insertion site. The deleted region includes a putative 110 bp exon. Northern blot analysis on adult cerebellar mRNA derived from homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:40243)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x SJL/J)F1
--
Insertion, Intergenic deletion
Recessive
1
1
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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