A neomycin resistance cassette was inserted into the coding region of the gene, disrupting it. Northern blots of brain and kidney RNA from homozygous mutant mice showed a lack of endogenous transcript for the targeted gene. (J:48441)
Basic Information
STOCK 129/Sv and C57BL/6J and SJL
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count