Restriction mapping showed that this allele comprises a 5.5 kb early transposon-like insertion element. RT-PCR based analysis shows that at least 8 different mutant transcripts are produced from the TWis allele. These transcripts bypass the mutated exon 7 splice donor site and no wild-type T transcripts are produced. (J:21263, J:107619)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
A/J
Spontaneous
Transposon insertion
Semidominant
1
3
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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