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A neomycin cassette replaced a genomic fragment containing sequences encoding the first 233 codons of the gene. Northern blot analysis demonstrated the absence of transcripts from this gene in brain and testis of homozygous mice and binding assays confirmed the absence of active protein. (J:52188)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
