A neomycin resistance cassette was inserted into exon 6 of the gene, causing truncation of the protein 179 amino acids from the C-terminal end. Northern analysis of RNA isolated from mutant embryos failed to show any transcript for the targeted gene. (J:53289)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count