Log In|Sign Up
EN
The molecular lesion responsible for the phenotype in pe8J mice consists of a 107-bp deletion in the Ap3b1 gene that alters the reading frame and produces a premature termination site. This results in the addition of 12 novel amino acids followed by a truncation eliminating 233 amino acids from the carboxy terminus. (J:52879, J:65643)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
