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This allele encodes a protein that lacks the final 18 amino acids (position 450 to 467) due to a nonsense mutation introduced into exon 10. The deletion corresponds to the last alpha helical structure (helix 12) of the ligand binding domain. A floxed neo cassette was inserted into intron 9 for selection. (J:50515)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
