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A neomycin cassette replaced an exon that encodes 41 amino acids that are located in the subdomain VI of the kinase domain. Immunoprecipitation and western blot analysis on protein extracts derived from fetal liver showed that no SYK protein was present in homozygous mice. (J:29797)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
