A neomycin cassette was inserted into exon 3. RT-PCR analysis did not detect any transcript produced from this allele in samples derived from liver or lung of homozygous mice. APRT protein activity was not detectable in eryothrocyte lysates or in liver extracts derived from homozygous mice. (J:33255)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
2
17

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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