A PGK-neomycin cassette was inserted into exon 3, immediately upstream of sequences required for DNA binding and protein dimerization. Absence of intact mRNA and protein were demonstrated by Northern and immunoblot analyses, respectively. (J:20132)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count