A neomycin cassette was inserted into the middle of exon 2, deleting the mature Edn3-encoding portion of the exon. No mature Edn3 protein was detected by EIA of kidney, brain, or intestine from homozygous mutant mice. (J:22207)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count