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A 0.7kb genomic fragment containing exons 1-3 was replaced by a lacZ gene and neomycin resistance cassette. This mutation placed the lacZ gene under the control of the Csf3 promoter elements. An activity assay demonstrated that the functional protein was not detectable in cultured medium derived from organ cultures of various tissues of homozygous mice. (J:20400)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
