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Approximately 20 copies of a Rous sarcoma virus long terminal repeat promoter, lacZ mini gene are integrated as a head to tail concatamer at a single site on mouse chromosome 14. There is in addition a deletion of 1.24 Mb of genomic DNA at the transgene insertion site. Fndc3a is contained in the deleted region. Comparative genome analysis of the 1.2 Mb region of chromosome 14 deleted in Fndc3asys mice with human 8p21 and 13q14 suggests that Fndc3a is the only gene mutated in Fndc3asysmice. (J:119576)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
