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It appears that hph1 may be a mutation in the mouse GTP cyclohydrolase gene, Gch1, although there are no coding sequence changes in the Gch1 open reading frame in hph1 mutants (J:20569). Homozygous mice carrying this mutation express significantly lower levels of GTP cyclohydrolase. (J:20569)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
