Cftr^tm1Unc

A neomycin selection cassette was inserted into exon 11 (exon 10 in legacy nomenclature numbering) at sequences corresponding to codon 489 of the encoded protein. The authors predict that a truncated protein with amino acid 488 changed from isoleucine to alanine and a stop codon at position 489 are produced from this allele. (J:2079)