The Map3k4 gene is located in a deletion extending from T, brachyury, to and including the Qk locus. Haploinsufficiency for Map3k4C57BL/6J in a specific genetic (C57BL/6J) background accounts for the T-associated sex reversal (Tas) phenotype. (J:10943, J:153050)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Not Applicable
Deletion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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