The mutation in the sex linked fidget mouse is an X chromosomal inversion with one breakpoint close to Pou3f4. This inversion selectively eliminates the expression of the Pou3f4 gene in the developing inner ear, but not the neural tube. The mutation was also shown to be allelic to Pou3f4tm1Cren. (J:59387)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C3H/HeH x 101/H)F1
Radiation induced
Inversion
Semidominant
1
4
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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