Ndc1^sks

A GG to TT substitution was found in exon 6 in a putative exonic splicing enhancer motif. As a result, the 109-bp sequence corresponding to exon 6 was deleted in mutant mice. This deletion creates a frameshift mutation resulting in premature termination at codon 225. Western blot analysis confirmed that no mature protein product was produced. (J:204898, J:222308)