Mafb^kr

There is a chromosomal inversion approximately 0.8 +/- 0.8cM in length very near the Mafb gene. The protein product of the normal gene is a transcription factor. The effect of the inversion appears to be to abolish transcription from the Mafb gene, not by physical disruption of the transcribed sequence, but by separation of coding sequences from a putative regulatory element or introduction of an inhibitory element. (J:4596, J:22020, J:83936)