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Southern blot analysis of genomic DNA showed that this allele was the result of the integration of a mutated c-fos transgene into the Reln locus with no gross structural rearrangements. Complementation analysis of offspring from a mating of mice hemizygous for the transgene and heterozygous for Relnrl showed 25% of the offspring had a reeler phenotype. (J:21534)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
