Log In|Sign Up
EN
Sequence analysis of genomic DNA from mutant mice showed showed a 7.1 kb LINE 1 sequence bordered at both ends by a direct repeat from the integration site within an exon that encodes the eigth EGF-like motif of the Reln protein. Nucleotide sequence analysis of showed that the LINE insertion caused this exon to be skipped during transcription leading to a 220 bp deletion in the Reln mRNA. (J:34099)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
