This phenotypic mutant was found to be allelic to ic by complementation testing. The mutation in the Lbric-J mouse was identified as 2 bp insertion at position 1088. This insertion results in a frame shift, changing amino acids 365-385, and creates a premature stop codon at amino acid position 386. (J:80915)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Spontaneous
Insertion
Recessive
1
6
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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