Insertion of a 4.4 kb recombinant plasmid carrying an altered dihydrofolate reductase gene creates an insertional mutation in this gene. The mutant is allelic to hotfoot ( Grid2ho ).
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count