Pomt1 - protein-O-mannosyltransferase 1

Predicted to enable mannosyltransferase activity. Acts upstream of or within extracellular matrix organization. Located in acrosomal vesicle and sarcoplasmic reticulum. Is expressed in several structures, including central nervous system; eye; gonad; heart; and hemolymphoid system gland. Used to study muscular dystrophy-dystroglycanopathy. Human ortholog(s) of this gene implicated in cardiomyopathy; cleft lip; lissencephaly; and muscular dystrophy (multiple). Orthologous to human POMT1 (protein O-mannosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]