Clp1 - CLP1, cleavage and polyadenylation factor I subunit

Predicted to enable polydeoxyribonucleotide kinase activity and polyribonucleotide 5'-hydroxyl-kinase activity. Involved in cerebellar cortex development. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of tRNA-intron endonuclease complex. Predicted to be active in nucleus. Is expressed in genitourinary system; liver lobe; and thymus primordium. Used to study pontocerebellar hypoplasia type 10. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 10. Orthologous to human CLP1 (cleavage factor polyribonucleotide kinase subunit 1). [provided by Alliance of Genome Resources, Apr 2022]