Mael - maelstrom spermatogenic transposon silencer

Predicted to enable sequence-specific DNA binding activity. Involved in DNA methylation involved in gamete generation; gene silencing by RNA; and piRNA metabolic process. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway in response to DNA damage; male gamete generation; and negative regulation of macromolecule metabolic process. Located in several cellular components, including chromosome; cytoplasmic ribonucleoprotein granule; and perinuclear region of cytoplasm. Is expressed in brain; early conceptus; and genitourinary system. Orthologous to human MAEL (maelstrom spermatogenic transposon silencer). [provided by Alliance of Genome Resources, Apr 2022]